Journal des troubles sanguins et de la transfusion

Abstrait

Can Plasma Donation Induce Coronary-Artery Thrombosis?

G Leurent, M Bedossa, C Camus, N Behar and P Mabo

Plasmaphereis donation is supposed to be safe. However, we report the case of a 47-year old man without any cardiovascular risk factors or medical history, except being a large volume plasmapheresis donor. Twenty four hours after a plasmapheresis, he presented a sudden death due to an acute myocardial infarction caused by a thrombotic lesion. The only funded etiology of this arterial thrombosis is the recent plasmapheresis donation. Although this technique is known to be safe, this report is the third one published about a life threatening arterial thrombosis due to apheresis donation, raising the interrogation about it harmlessness.