Journal de la technologie microbienne et biochimique

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Cholesterol Degradation Effect Analyzed using Marine Cyanobacterial Species Spirulina subsalsa

Kollimalai Sakthivel and Kandasamy Kathiresan

In this study was designed to understand the mechanisms of cholesterol degradation by cyanobacterial species Spirulina subsalsa. We analyzed the degradation of cholesterol in albino mice using basal feed diet (control) and different concentration (1%, 2% and 4%) of cyanobacterial diet. Cholesterol was estimated from the control and cyanobacterial fed to the albino mice. Blood cholesterol level reduced 8.1, 24.3, 30.6 % in 1, 2 and 4% cyanobacterial diet respectively. Phycobiliproteins are the most abundant soluble protein complexes in cyanobacteria and phycocyanin have 75% in phycobiliprotein. We concluded, phycocyanin was major role for cholesterol degradation in albino mice.