Effrosyni Grosi*, Anthoula Tsolaki, Iordanis Saoulidis, Eleni Liouta, Christos Savopoulos, Isidora Bakaimi, Martha Spilioti
The COVID-19 pandemic has made a major impact worldwide. The vaccines production was a huge biotechnology achievement empowering the defense against this fatal threat. However, as billions of shots have been administered, some safety issues have been raised. We present a case of a 55-year-old patient with a history of CLL (Chronic Lymphocytic Leukemia), who had encephalitis seventeen days post vaccination. Although the benefits outweigh the risk of vaccination at this point, all the rare and serious adverse events should be reported. The significance of such reports is even greater when refer to special patient sub-groups, regarded as immunocompromised.