Journal des maladies tropicales et de la santé publique

Abstrait

Identification of Antibodies against Dengue Virus in Domestic Dogs: A Potential Reservoir at Home?

Lopez-Monteon Aracely, Benitez-Villa Grecia Evelyn, Marquez-Fernandez Abner Julian, Guzman-Gomez Daniel, Maldonado-Renteria Mathywz de Jesus, Ramos-Ligonio Angel*

Background: Mosquitoes are efficient vectors of pathogenic arboviruses of importance to man because they remain infected throughout their life without developing the infection. These vector-borne diseases affect humans and also can affect animals.

Objective: To evaluate the presence of anti-dengue antibodies in domestic dogs from a rural area of Veracruz, Mexico.

Materials and Methodology: Serum samples were analyzed for dengue virus infection using three different ELISA tests (Panbio- Dengue IgG, Platelia Dengue NS1 antigen, in-house system anti-rNS3, and western blot assay.

Results: An overall seroprevalence of 53.2% was obtained and based on the identification of NS1 protein, 29.8% infected dogs were found.

Conclusions: The dog is capable of inducing a humoral immune response on proteins of DENV, which requires further investigation of the role of the dog as a host in DENV infection