Indexé dans
- Ouvrir la porte J
- Genamics JournalSeek
- JournalTOCs
- Répertoire des périodiques d'Ulrich
- RechercheRef
- Université Hamdard
- EBSCO AZ
- OCLC - WorldCat
- Invocation de Proquête
- Publions
- Fondation genevoise pour la formation et la recherche médicales
- Pub européen
- Google Scholar
Liens utiles
Partager cette page
Dépliant de journal
Revues en libre accès
- Agriculture et aquaculture
- Alimentation et nutrition
- Biochimie
- Bioinformatique et biologie des systèmes
- Business & Management
- Chimie
- Génétique et biologie moléculaire
- Immunologie & Microbiologie
- Ingénierie
- La science des matériaux
- Neurosciences & Psychologie
- Science générale
- Sciences cliniques
- Sciences environnementales
- Sciences médicales
- Sciences pharmaceutiques
- Sciences vétérinaires
- Soins infirmiers et soins de santé
Abstrait
Management of Blood Transfusion in a Patient Carring Anti-Rh18 Associated with the RHD*Weak D 4.2.2/RHCE*ceAR Haplotype
Costa SSM, Chiba AK , Cruz BR , Fabron Jr A, Chiattone CS , Langhi Jr. DM and Bordin JO
The RH blood group system is the most polymorphic and immunogenic among blood groups. Variant Rh antigens have been found with high frequencies in African descendants persons. The DAR-ceAR haplotype results from the rearrangement of the RHCE gene with the internal sequences of the RHD gene that give rise to an altered Rh protein and may produce a clinically significant antibody. We report a case of anti-RH18 detected in a female patient with sickle cell trait. Serologic and molecular investigations were performed to identify RH variants from the propositus and her relatives. The results of genomic DNA analysis showed the propositus carrying the haplotype RHD*weak D 4.2.2/RHCE*ceAR, as well as her father and sister.