Abdelwahid Ali Mohamed, Qusay Eltayeb
Rota virus diarrhea is a global health problem leading to high morbidity and mortality among children less than five years, the implementation of Rotavirus vaccine has made a change in this area. This study examined the impact of Rotavirus vaccine on prevalence of Diarrhea in Omdurman pediatric hospital, Khartoum, Sudan. A total of 368 children less than or equal to three years of age suffering from watery non bloody diarrhea were investigated by taking stool sample and examined by sandwich enzyme linked immunosorbent assay ((ELISA) to detect the Rotavirus antigen. Out of the 368 patient investigated, 28% tested positive for Rotavirus antigen, the highest rate of infection (49.5 %) was found among patient less than one year of age, patient with very sever disease were more in those whom were partially vaccinated (70.6%). Introduction of Rotavirus vaccine was found to decrease the prevalence of Rotavirus diarrhea from 33% to 28 %.