Pharmaceutica Analytica Acta

Abstrait

The Research on Compliance with ARV Treatment, Related Factors of Noncompliance with ARV in HIV Patients, and Assessment of Intervention Results by Communication at the Thot Not District In 2021

Lam Phuc Duong

Background: Antiretroviral therapy adherence is a critical factor in antiretroviral therapy. Antiretroviral therapy is a lifelong treatment, so it is difficult to adhere to treatment. It is essential to identify factors that lead to non-adherence to treatment in order to communicate interventions to improve adherence.

Research objectives: Determine the percentage of HIV-infected patients who adhere to ART; comprehend the factors associated with HIV-infected patients not adhering to treatment; and participate in media interventions on HIV-infected people who do not adhere to treatment at Thot Not General Hospital in 2020-2021.

Subjects and methods: A cross-sectional descriptive study without a control group on 333 HIV-infected patients on ART at Thot Not District General Hospital.

Results: 62.8% of HIV-infected patients adhered to antiretroviral therapy. Follow-up compliance on time was 79.3%; taking the full dose was 77.5%; on time, 74.5%; correctly, 77.5%; and correctly, 92.5%. There is a relationship between non-adherence to treatment and marital status, gender, and personal income. After the intervention, the adherence rate increased to 81.7%. In which 91% of patients had an on-time follow-up examination, 89.5% took the full dose, 87.4% were on time, 95.2% used the correct method, and 97.9% took the correct medication

Conclusion: The rate of HIV-infected patients who adhere to ARV treatment is 62.8%. There is a relationship between non-adherence to treatment and marital status, gender, personal income. The effectiveness of the intervention is 30% (p<0.001).